Lotrisone cream (Clotrimazole/Betamethasone)

With two active ingredients, Lotrisone can help treat certain inflamed fungal skin infections. Clotrimazole helps control fungal growth, while betamethasone, a corticosteroid, helps reduce redness, itching, and inflammation in the affected area. In Canada, this combination may be discussed in dermatology or primary care when assessing inflamed fungal skin conditions.

When do you need Lotrisone?

Lotrisone may be used for certain fungal skin infections. To find out which organism is causing your symptoms, you should see a Canadian clinician. You may also need tests to identify the cause.

For yeast-related skin infections, Lotrisone may be used only when the skin is affected. It should not be used for vaginal yeast infections or on mucous membranes. A typical course may last up to 2 weeks with twice-daily application, depending on the condition and your clinician's advice.

This medicine is commonly prescribed for ringworm, jock itch, and athlete's foot.

Can Lotrisone be used for eczema?

No. Eczema is not a fungal infection, so Lotrisone is not appropriate and may be harmful if used incorrectly.

Dosage and instructions for use

Lotrisone is available as a cream or lotion. Both typically contain clotrimazole 1% and betamethasone 0.05%, so you and your healthcare provider in Canada can decide which formulation is best.

How long treatment lasts depends on your progress and the condition being treated. For ringworm, Lotrisone is often used twice daily for at least 1 week. Even if symptoms improve sooner, complete the course as directed to help reduce the chance of the infection coming back.

If symptoms are still present after 1 week, treatment may continue for another 7 days, depending on clinical advice. A similar approach may be used for jock itch. When treating a fungal infection in the groin, make sure your underwear is not tight and is made from natural fabrics to help reduce sweating and moisture.

Athlete's foot can be harder to treat and may require up to 4 weeks. The cream or lotion is usually applied twice a day, in the morning and at bedtime.

Gently rub the medicine into the affected areas of skin.

Can Lotrisone be used on the face?

Use it on the face only if a clinician specifically advises you to. Avoid getting the cream or lotion in your eyes, nose, or mouth.

Do not use more than 45 g of cream or 45 mL of lotion per week unless directed by a clinician, as using too much can increase the risk of side effects.

Who shouldn't use Lotrisone?

Some people should avoid Lotrisone. This includes people with:

• Known hypersensitivity to clotrimazole, betamethasone, or any inactive component of the medication;
• Melanoma;
• Skin cancer;
• Hemangioma or other skin tumours;
• Circulation problems;
• Immunosuppression or low immunity.

Lotrisone is contraindicated in people younger than 17 years. Older adults should use this medicine under close supervision, as the risk of side effects may be higher. Never use this medicine by mouth or vaginally. Avoid getting it in the eyes and nose.

During pregnancy, Lotrisone should be used only if the potential benefits outweigh the risks and if a clinician advises it. If you are breastfeeding, speak with a healthcare professional before using it.

What side effects may occur?

This medicine is usually well tolerated when used as directed. However, side effects can happen. The most common local reactions include:

• Dry skin;
• Itching and redness;
• Peeling;
• Burning;
• Rash.

These reactions are usually limited to the areas where the medication is applied. If you have these symptoms, contact your clinician to discuss what to do next.

Rare but potentially serious effects have also been reported. Get medical advice promptly if you notice:

• Fever;
• Difficulty urinating;
• Skin discoloration or thinning;
• Stretch marks or acne-like eruptions;
• Headache;
• Nausea or vomiting.

This is not a complete list of possible reactions. Ask a pharmacist or clinician for more information, and seek urgent medical help if your symptoms are severe or concerning.