AntiInfectiveMeds
Since 2010
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 10 | C$4.52 | - | C$45.22 | |
| 20 | C$2.42 | C$42.00 | C$48.44 | |
| 30 | C$1.78 | C$82.18 | C$53.48 | |
| 60 | C$1.02 | C$210.28 | C$61.04 | |
| 90 | C$0.74 | C$340.06 | C$66.92 | |
| 120 | C$0.39 | C$495.32 | C$47.32 | |
| 180 | C$0.36 | C$748.86 | C$65.10 | |
| 270 | C$0.34 | C$1,127.98 | C$92.96 | |
| 360 | C$0.34 | C$1,504.72 | C$123.20 |
| Quantity | Price per tablet | You save | Total price | |
|---|---|---|---|---|
| 10 | C$5.05 | - | C$50.54 | |
| 20 | C$2.72 | C$46.62 | C$54.46 | |
| 30 | C$2.05 | C$90.02 | C$61.60 | |
| 60 | C$0.72 | C$260.26 | C$42.98 | |
| 90 | C$0.66 | C$395.78 | C$59.08 | |
| 120 | C$0.62 | C$532.14 | C$74.34 | |
| 180 | C$0.58 | C$805.98 | C$103.74 | |
| 270 | C$0.56 | C$1,213.66 | C$150.92 | |
| 360 | C$0.55 | C$1,623.02 | C$196.42 |
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over C$420.00 | Estimated delivery to Canada: 4-7 days |
| Standard Free for orders over C$280.00 | Estimated delivery to Canada: 14-21 days |
| Country | Brand Names |
|---|---|
| Canada | Apo-Ampi |
Ampicillin tablets are a penicillin-class (beta-lactam) antibiotic used to treat certain bacterial infections when the bacteria are susceptible. Use them exactly as prescribed-antibiotics do not work for colds, flu, or other viral illnesses.
Ampicillin is a beta-lactam antibiotic. It kills bacteria and works in a similar way to penicillin G (benzylpenicillin). As an aminopenicillin with an amino side chain attached to the basic penicillin structure, ampicillin can better penetrate the outer membrane of some Gram-negative bacteria and has a broader spectrum of activity.
Ampicillin is similar to benzylpenicillin in its activity against Gram-positive organisms, including Streptococcus pneumoniae and other streptococci, but with the possible exception of activity against Enterococcus faecalis, it may be slightly less potent than benzylpenicillin. Listeria monocytogenes is generally susceptible. The Gram-negative cocci Moraxella catarrhalis (Branhamella catarrhalis), Neisseria gonorrhoeae, and N. meningitidis may be susceptible, depending on local resistance patterns.
Ampicillin is more active than benzylpenicillin against some Gram-negative bacilli, including Haemophilus influenzae and Enterobacteriaceae such as Escherichia coli, Proteus mirabilis, Salmonella and Shigella spp. It is not active against Pseudomonas aeruginosa.
Ampicillin also has activity similar to benzylpenicillin against other organisms, including many anaerobes and Actinomyces spp.
Activity with other antimicrobials. Synergy has been shown between ampicillin and aminoglycosides against some organisms, including enterococci. Variable effects, ranging from synergy to antagonism, have been reported between ampicillin and other beta-lactams, bacteriostatic drugs such as chloramphenicol, and rifampicin.
Resistance. Like benzylpenicillin, ampicillin is inactivated by beta-lactamases, although other mechanisms may be responsible for resistance in some species. Resistance rates vary by region; many strains of staphylococci and some Gram-negative organisms may be resistant.
Ampicillin is relatively resistant to inactivation by gastric acid and is moderately well absorbed from the gastrointestinal tract after oral doses. Food can interfere with ampicillin absorption, so doses are often taken on an empty stomach (for example, at least 30 minutes before meals). Peak plasma concentrations are reached in about 1 to 2 hours; after a 500-mg oral dose, reported peak levels range from 3 to 6 mcg/mL.
Ampicillin is widely distributed and crosses the placenta; small amounts pass into breast milk. There is little diffusion into the CSF except when the meninges are inflamed. About 20% is bound to plasma proteins, and the plasma half-life is about 1 to 1.5 hours, but this may be longer in neonates, older adults, and patients with renal impairment.
Ampicillin is metabolized to some extent to penicilloic acid and is eliminated mainly by the kidneys. Renal clearance occurs partly by glomerular filtration and partly by tubular secretion, and it is reduced by probenecid.
In Canada, ampicillin tablets are used to treat a variety of infections caused by susceptible organisms. In Canadian practice, whenever possible, treatment should be guided by culture and susceptibility results.
| Feature | Ampicillin (tablets) | Amoxicillin |
|---|---|---|
| Drug class | Aminopenicillin (beta-lactam) | Aminopenicillin (beta-lactam) |
| Absorption and food | Food can reduce absorption; often taken on an empty stomach (for example, at least 30 minutes before meals) | Generally better oral absorption; can usually be taken with or without food (follow your product label or prescriber's instructions) |
| Dosing convenience | Often requires more frequent dosing (commonly every 6 hours, depending on the infection) | Often requires less frequent dosing (commonly every 8-12 hours, depending on the infection) |
| Penicillin allergy | Both are penicillins. Avoid them if you have a serious penicillin allergy (for example, anaphylaxis). Tell your clinician about any past reactions. | |
Take ampicillin tablets exactly as prescribed. Because food can reduce absorption, they are often taken on an empty stomach (for example, at least 30 minutes before meals). Finish the full course unless your prescriber tells you to stop.
Common side effects may include diarrhea, nausea, vomiting, and skin rash. Get urgent medical help if you have signs of a severe allergic reaction (for example, swelling of the face or throat, trouble breathing), severe skin reactions, or severe or persistent diarrhea, which can be a sign of Clostridioides difficile-associated diarrhea.
Pregnancy: animal studies with penicillins have not shown harm to the fetus, but there are no adequate, well-controlled studies in pregnant women. Use during pregnancy only if clearly needed and as prescribed.
Breastfeeding: ampicillin-class antibiotics are excreted in breast milk and may cause sensitization in the infant; use with caution and contact a clinician if the baby develops a rash, diarrhea, or thrush.
Dose adjustment may be needed in renal impairment. Follow your prescriber's instructions if you have kidney disease or are receiving dialysis.
Store at 20°C to 25°C (68°F to 77°F). Keep the container tightly closed and out of reach of children.
My last ampicillin order looked different from the capsules I received this time. What should I compare before taking them?
Compare the active ingredient, strength, capsule dosage form, manufacturer, package label, lot number, expiry date, and any capsule imprint. Different manufacturers can use different colours or markings, but do not take the capsules if the label, strength, seal, or physical condition appears wrong.
My ampicillin package was delivered in Ottawa during a very cold spell. What should I check before using the capsules?
Keep the package and check that the capsules and packaging are dry, intact, and within the labelled expiry date. Store capsules at 20°C to 25°C in a tightly closed container protected from moisture.
I recently had mononucleosis, and I have now been prescribed ampicillin for a possible bacterial infection. Is there anything important to know?
Ampicillin can cause a prominent rash in people with infectious mononucleosis, often due to Epstein-Barr virus. Make sure the prescriber knows about the recent mononucleosis before starting treatment so the diagnosis and antibiotic choice can be reviewed.
| Active ingredient | Ampicillin |
|---|---|
| Drug class | Penicillin antibiotic |
| Dosage form | Capsule |
| Available strengths | 250 mg, 500 mg |
| Route | Oral |
| Storage | Store capsules at 20°C to 25°C in a tightly closed container, protected from moisture. |
| ATC code | J01CA01 |
This product has 8 ratings, but only 6 written reviews so far. Share your experience and help other customers.
The Ampicillin order arrived as expected.
The order arrived within the expected delivery period.
A pack of 90 was practical. It was the size I needed.
The capsules were a different colour from the pharmacy-bought brand, as expected. I cared more that both contained ampicillin.
I'm pleased with the product I chose.
Good value for the Ampicillin order.
