AntiInfectiveMeds
Since 2010
| Quantity | Price per capsule | You save | Total price | |
|---|---|---|---|---|
| 30 | C$1.01 | - | C$30.38 | |
| 60 | C$0.79 | C$13.16 | C$47.60 | |
| 90 | C$0.73 | C$25.62 | C$65.52 | |
| 120 | C$0.64 | C$44.66 | C$76.86 | |
| 180 | C$0.58 | C$78.40 | C$103.88 | |
| 240 | C$0.53 | C$116.62 | C$126.42 | |
| 360 | C$0.47 | C$195.44 | C$169.12 |
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over C$420.00 | Estimated delivery to Canada: 4-7 days |
| Standard Free for orders over C$280.00 | Estimated delivery to Canada: 14-21 days |
| Country | Brand Names |
|---|---|
| Canada | APO-DOXY |
Doxycycline is a tetracycline antibiotic used to treat a wide range of susceptible bacterial infections. In Canada, it is also used for selected preventive regimens, such as travel medicine, and for other specialist-guided uses.
| Dosage form | Typical use | Key practical notes | Where you usually see it |
|---|---|---|---|
| Tablets / capsules | Most outpatient treatment courses | Take with a full glass of water; don't lie down right after | Home / pharmacy |
| Oral suspension (liquid) | People who have trouble swallowing pills | Shake well; measure doses carefully; follow the label storage directions | Home / pharmacy |
| Delayed-release formulations | Selected uses/products; may be easier on the stomach for some patients | Follow the product-specific instructions (don't assume it is identical to immediate-release) | Home / pharmacy |
| IV (intravenous) | When oral therapy isn't feasible or in specialist settings | Given by healthcare professionals | Hospital / clinic |
| What you take | Why it matters | Practical timing | Notes |
|---|---|---|---|
| Milk/dairy | May affect absorption for some products or patients | If possible, avoid taking it at the same time | If nausea happens, taking doxycycline with a light meal may help |
| Antacids (Ca/Mg/Al), bismuth | Can bind doxycycline and reduce absorption | Separate by a few hours (follow pharmacist or label guidance) | Common culprits: heartburn medications |
| Iron, zinc, magnesium, calcium supplements | Can bind doxycycline and reduce absorption | Separate by a few hours (follow pharmacist or label guidance) | Includes many multivitamins |
| Food (general) | May improve stomach tolerability | OK with food if needed | Avoid lying down after taking a dose |
| Situation | What to do | What to avoid | When to get advice |
|---|---|---|---|
| You remember soon after the scheduled time | Take the missed dose as soon as you remember | Don't take it without water or right before lying down | If you're unsure about spacing with minerals or antacids, ask a pharmacist |
| It's almost time for your next dose | Skip the missed dose and take the next dose at the usual time | Do not double the next dose | If you miss more than one dose, ask your prescriber what to do |
| You vomit soon after a dose | Ask a pharmacist or clinician whether you should repeat the dose | Don't automatically take another dose without guidance | Get advice if vomiting is persistent or severe |
Doxycycline is a tetracycline derivative with uses similar to tetracycline. It may sometimes be preferred to other tetracyclines for susceptible infections because its absorption is fairly reliable and its long half-life allows less frequent dosing, often once daily. It also has the advantage that it can be used, with care, in patients with renal impairment. However, relatively high doses may be needed for urinary tract infections because of its low renal excretion.
Tooth infection (dental infection): Antibiotics are not a substitute for dental procedures (for example, drainage or definitive dental treatment). In many cases, urgent dental treatment is prioritized in Canada, and antibiotics are reserved for cases with systemic involvement or a higher risk of spread. A Canadian clinician or dentist may prescribe an antibiotic based on the suspected organisms and your allergy history.
| Common request | Reality | What to do instead |
|---|---|---|
| 'Antibiotics for a toothache' | Dental pain often needs dental treatment (for example, drainage or a procedure), not just antibiotics | See a dentist urgently, especially if you have swelling or fever |
| 'It will treat any STI' | Doxycycline is not first-line for gonorrhea in current US guidance | Get tested and follow guideline-based treatment |
| "It works for colds/flu" | Colds and flu are usually viral; antibiotics do not help | Supportive care; see a clinician if symptoms are severe or getting worse |
| 'I can use leftovers whenever I feel sick' | Using the wrong drug, dose, or duration increases the risk of treatment failure and resistance | Use only a prescribed course for your current condition |
Doxycycline is usually given by mouth as the base or one of its salts, usually the hyclate. Doses are expressed in terms of doxycycline; doxycycline hyclate 115 mg is equivalent to about 100 mg of anhydrous doxycycline.
The usual adult dose, taken by mouth or given intravenously, is 200 mg of doxycycline on the first day (as a single dose or in divided doses), followed by 100 mg daily. In severe infections, the initial dose may be continued throughout the course of treatment, as prescribed.
Gonorrhea note (Canada): Doxycycline is not a first-line treatment for gonorrhea in current Canadian guidance. Recommended therapy typically includes ceftriaxone; doxycycline may be used only when a clinician is also treating possible chlamydial infection and when appropriate.
For syphilis in penicillin-allergic patients, doxycycline 100 to 200 mg twice daily is given by mouth for at least 14 days; some authorities suggest the same dose for 28 to 30 days in patients with late latent disease (follow specialist guidance).
For malaria prevention, doxycycline chemoprophylaxis should begin 1-2 days before travel to endemic areas, be taken once daily during travel, and continue daily for 4 weeks after leaving the endemic area (follow travel medicine guidance).
Minerals and antacids, especially products containing calcium, magnesium, aluminum, iron, zinc, or bismuth, can reduce doxycycline absorption-use the timing guide above. Some medicines that induce liver enzymes (for example, rifampicin and certain antiepileptics) may reduce doxycycline levels. Tell your prescriber about all medications and supplements you take.
Occasional alcohol use is not known to cause a disulfiram-like reaction with doxycycline. However, chronic heavy alcohol use may reduce doxycycline exposure, which could lower how well it works. If you drink heavily or have alcohol use disorder, discuss this with your prescriber.
Gastrointestinal side effects with doxycycline are reported to be less common than with tetracycline, and doxycycline may also cause less tooth discolouration. Esophageal ulceration can be a particular problem if capsules or tablets are taken with too little fluid or while lying down. Doxycycline should be taken with a full glass of water, while upright, and well before bedtime. Dispersible tablets or liquid formulations should be used in elderly patients, who may be at greater risk of esophageal injury. Unlike many tetracyclines, doxycycline does not appear to accumulate in patients with impaired renal function, and worsening of impairment may be less likely.
| Practical point | Doxycycline | Minocycline | Tetracycline |
|---|---|---|---|
| Dosing convenience | Often once daily (depends on the indication) | Often once or twice daily (depends on the indication) | Often multiple daily doses |
| Food/minerals effect | Generally less affected by food than tetracycline, but minerals and antacids can still interfere | Minerals and antacids can interfere | More likely to be affected by food and minerals |
| Photosensitivity | Can occur | Can occur | Can occur |
| Vestibular effects (dizziness/vertigo) | Less commonly emphasized than with minocycline | More commonly reported | Can occur |
| Esophageal irritation risk | Notable if taken without enough water or right before lying down | Also possible | Also possible |
For the general pharmacokinetics of tetracyclines, see Tetracycline. Doxycycline is absorbed from the gastrointestinal tract; absorption and peak levels may vary by formulation and by study, and can be affected by taking it with multivalent cations (for example, calcium, iron, magnesium, or aluminum).
About 80 to 95% of doxycycline in the circulation is reported to be bound to plasma proteins. Its biological half-life varies from about 12 to 24 hours. Doxycycline is more lipid-soluble than tetracycline. It is widely distributed in body tissues and fluids.
Most of a dose of doxycycline is excreted in the feces after chelation in the intestines. Removal of doxycycline by hemodialysis is insignificant.
In children, the effects on teeth should be considered. Because tetracyclines can affect tooth development, doxycycline use in children 8 years of age or younger should be limited to situations where the potential benefits are expected to outweigh the risks (for example, severe or life-threatening infections as directed by a clinician).
In Canada, dosing in children, when used, is weight-based; follow clinician and public health guidance for specific indications (for example, anthrax exposure).
Veterinarians may advise avoiding giving it with products that contain calcium, magnesium, aluminum, iron, or zinc because these can reduce absorption. As with other tetracyclines, extra caution is used in very young animals because of possible effects on developing teeth and bones. Contact a veterinarian promptly if a pet develops persistent vomiting, diarrhea, or other concerning symptoms during treatment.
Store at room temperature: 20°C to 25°C (68°F to 77°F). Short-term temperature changes are allowed: 15°C to 30°C (59°F to 86°F). Keep the container tightly closed, protected from light, and out of reach of children.
Doxycycline is a widely used tetracycline antibiotic with convenient dosing and generally reliable absorption. Take it with plenty of water while sitting or standing, avoid taking it at the same time as mineral-containing antacids or supplements, and store it at controlled room temperature. Follow your prescriber's directions, especially for dental infections (where definitive dental treatment is key), sun sensitivity, and if you drink alcohol heavily.
My Vibramycin package arrived in Kitchener during a very cold spell. What should I check before taking the capsules?
Check that the package and capsules are dry, intact, and within the labelled expiry date, then store them at 20°C to 25°C, protected from light and moisture.
I live in Yellowknife. How can I find out whether Vibramycin capsules can be shipped to my address before I order?
Enter the full delivery address and postal code during checkout to see the delivery options we offer for your destination before ordering.
Before ordering from Winnipeg, can I use my postal code to see whether these doxycycline capsules can be shipped to me?
Yes. Enter your Winnipeg postal code and delivery address at checkout to check whether the product can be shipped to your location before completing the order.
I need to avoid certain capsule ingredients. Where can I check the details on the package I receive?
Check the package label and any enclosed product information for the active ingredient, strength, dosage form, manufacturer, and listed non-medicinal ingredients. These details may vary between supplied products, so the received label is the appropriate reference.
I drive for work and am starting doxycycline capsules. Is it okay to drive after taking a dose?
Doxycycline is not usually sedating, but dizziness, vertigo, or blurred or double vision can occur. Do not drive or operate machinery while affected; significant headache or visual changes need prompt medical assessment.
| Active ingredient | Doxycycline |
|---|---|
| Drug class | Tetracycline antibiotic |
| Dosage form | Capsule |
| Available strengths | 100 mg |
| Route | Oral |
| Storage | Store at 20°C to 25°C; excursions permitted from 15°C to 30°C. Protect from light and moisture. |
| ATC code | J01AA02 |
This product has 54 ratings, but only 4 written reviews so far. Share your experience and help other customers.
I'd order Vibramycin again.
I received my order; all good.
Several package sizes were available. The 30-unit package suited this order.
Everything went smoothly.
