Zyvox (Linezolid)
Dosages
Zyvox 600 mg
| Quantity | Price per tablet | Total price | |
|---|---|---|---|
| 30 | C$10.24 | C$307.27 | |
| 60 | C$9.76 | C$585.47 |
Payment & Shipping
Your order is carefully packed and ships within 24 hours. Here is what a typical package looks like.
Sized like a regular personal letter (approximately 24x11x0.7 cm), with no indication of what is inside.
| Shipping Method | Estimated delivery |
|---|---|
| Express Free for orders over C$415.23 | Estimated delivery to Canada: 4-7 days |
| Standard Free for orders over C$276.82 | Estimated delivery to Canada: 14-21 days |
Discount Coupons
- Canada Day - July 1, 2026 10% CANADADAY10
- Boxing Day - December 26, 2026 12% BOXING12
Brand Names
| Country | Brand Names |
|---|---|
 Austria | Zyvoxid |
 Bangladesh | Arlin |
 Canada | Zyvoxam |
 Czechia | Dilizolen |
 Egypt | Averozolid |
 France | Zyvoxid |
 Georgia | Anzolid |
 Germany | Zyvoxid |
 India | Linospan Linox Lizolid Lizomac Megazolid |
 Ireland | Zyvoxid |
 Italy | Zyvoxid |
 Kenya | Amizole 500 |
 Netherlands | Dilizolen Grampolid Zyvoxid |
 Poland | Anozilad Dilizolen Zyvoxid |
 Portugal | Zyvoxid |
 Serbia | Anozilad |
 Slovakia | Dilizolen |
 Spain | Zyvoxid |
 Sweden | Zyvoxid |
| Manufacturer | Brand Names |
|---|---|
| Cipla Limited | Linospan |
Description
Zyvox (linezolid) is an oxazolidinone antibiotic used to treat certain serious infections caused by susceptible Gram-positive bacteria. In Canada, it may be prescribed in hospital or specialist care when this type of antibiotic is clinically appropriate.
Drug class
Linezolid belongs to the oxazolidinone class of antibiotics.
How it works
Linezolid blocks bacterial protein synthesis at an early stage by preventing formation of the 70S initiation complex.
What Zyvox tablets treat (and what they do not)
| Disease / condition (A-Z) | Zyvox tablets |
|---|---|
| Community-acquired pneumonia (CAP) | + |
| Complicated skin and skin structure infections | + |
| Diabetic foot infection (without concomitant osteomyelitis) | + |
| Gonorrhea | - |
| Gram-negative infections (e.g., E. coli, Pseudomonas) | - |
| Hospital-acquired / nosocomial pneumonia (HAP) | + |
| Osteomyelitis | - |
| Pressure ulcers (decubitus ulcers) | - |
| Uncomplicated skin and skin structure infections | + |
| Urinary tract infection (UTI) | - |
| VRE (Enterococcus faecium) infection, including cases with concurrent bacteremia | + |
| Viral infections (flu/common cold) | - |
| Yeast or other fungal infections | - |
Limitations of use (Canada): Zyvox is not indicated for the treatment of Gram-negative infections. If a Gram-negative pathogen is suspected or confirmed, appropriate treatment should be started.
Indications (US labeling)
Zyvox tablets are used for certain infections caused by susceptible Gram-positive bacteria, including pneumonia (hospital-acquired and community-acquired), skin and skin structure infections (complicated and uncomplicated), and vancomycin-resistant Enterococcus faecium (VRE) infections, including cases with concurrent bacteremia.
Tablet strength
- Tablet: 600 mg (film-coated).
Can you split the tablet?
Zyvox 600 mg tablets are film-coated and are not described as scored in Canadian product information. Because of this, splitting or crushing them is generally not recommended unless a clinician specifically tells you to do so.
Why is Zyvox expensive? Are there alternatives?
Cost can be affected by brand pricing, manufacturing and supply chain factors, and market conditions. Depending on the infection and culture/susceptibility results, clinicians may choose alternatives. Health Canada-authorized generic linezolid tablets are available in Canada and may cost less than the brand product in some settings.
What medicines is it used with?
Zyvox may be used on its own for confirmed susceptible Gram-positive infections. If an infection is mixed or a Gram-negative pathogen is suspected, clinicians may prescribe Zyvox together with other antibiotics that cover Gram-negative organisms and, when needed, anaerobes. The exact combination depends on the site of infection, its severity, and local resistance patterns.
Drug interactions
Linezolid is a reversible, nonselective MAO inhibitor (MAOI). It can interact with adrenergic drugs, which may raise blood pressure, and serotonergic drugs, which may increase the risk of serotonin syndrome. Tell your clinician about all prescription, over-the-counter, and herbal products you use.
Contraindications
| Contraindication | What it means |
|---|---|
| Hypersensitivity to linezolid (or any component of the product) | Do not use if you have a known serious allergy to linezolid or any of the product ingredients. |
| Use with MAO inhibitors (or within 2 weeks of stopping an MAOI) | Do not use with MAOIs (e.g., phenelzine, isocarboxazid, selegiline) or within 2 weeks of stopping them because of the risk of interactions. |
Tyramine (food interaction)
Because linezolid has MAOI activity, avoid consuming large amounts of tyramine-rich foods and drinks during treatment. Examples include aged cheeses, cured, aged, or improperly stored meats, fermented foods (including some soy and yeast products), and certain alcoholic drinks (such as some beers and red wine). Seek medical help if you develop a severe headache, flushing, or a marked rise in blood pressure.
Side effects and key precautions
Common side effects include diarrhea, nausea/vomiting, and headache.
Important warnings and precautions include myelosuppression (including thrombocytopenia; complete blood counts are commonly monitored weekly), peripheral and optic neuropathy (reported mainly with treatment longer than 28 days), lactic acidosis, seizures, and C. difficile-associated diarrhea. Report unusual bruising or bleeding, severe or persistent diarrhea, or new vision symptoms right away, including blurred vision or changes in visual acuity or colour vision.
Storage
Store at 25°C (77°F); excursions permitted to 15-30°C (59-86°F).
